Million Dollar Bike Ride Grants for STXBP1

Two $69,708 grants for STXBP1 Research!

Letter of Interest (LOI) Applications are Due Friday, September 20th, 2024 by 8pm ET


Lulu’s Crew / Team STXBP1 rode for the 6th year --raising a more than $139K in funds for STXBP1 research-- in the Million Dollar Bike Ride, organized by the Orphan Disease Center.

Projects addressing any stage of pre-clinical to clinical development for STXBP1 disorders will be considered. Areas of priority interest include, but are not limited to:

  1. Understanding pathomechanisms and genotype-phenotype relationships of STXBP1 disorders. This may include the development of novel murine or iPSC-based models to determine pathomechanisms of missense variants.

  2. Development of clinical trial readiness, including identification of novel biomarkers and non-seizure clinical endpoints and assessments.

  3. Determining the trajectory of STXBP1 disorders from pediatric to adult presentations.

  4. Developing or advancing novel therapeutic approaches to correct STXBP1 disorders


These grants are made possible by Lulu’s Crew / Team STXBP1.



Information on STXBP1 research projects previously funded through the Million Dollar Bike Ride and Lulu’s crew is here: https://www.stxbp1disorders.org/researchfundingrecipients